
← Huberman Lab
Essentials: The Science of Learning & Speaking Languages | Dr. Eddie Chang
May 21, 2026 · 33 min
In this Huberman Lab Essentials episode, my guest is Dr. Eddie Chang, MD, a neurosurgeon and Chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF). We discuss the neural circuits underlying speech and language, including how the brain controls the larynx, vocal folds and articulators to shape breath into words. We also explore his pioneering work on speech neural prosthetics — brain-machine interfaces that allow paralyzed patients to communicate by decoding neural activity into speech and avatar-driven facial expressions. Additionally, we examine the neurobiology of stuttering, the role of auditory feedback in fluent speech, and the broader ethical questions surrounding brain augmentation technologies.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
AG1: https://drinkag1.com/huberman
BetterHelp: https://betterhelp.com/huberman
Function: https://functionhealth.com/huberman
Timestamps
(00:00:00) Speech & Language
(00:00:23) Speech vs Language, Pragmatics, Semantics & Syntax
(00:03:11) Larynx, Vocal Folds & Shaping the Breath
(00:05:35) Crying & Laughter, Vocalizations vs Speech
(00:06:37) Sponsor: Function
(00:08:52) Paralysis, Brainstem Stroke, ALS & Locked-In Syndrome
(00:10:52) BRAVO Trial, Pancho & First Patient
(00:12:31) Brain Surgery, Electrode Array & Decoding Speech
(00:14:34) AI, 50-Word Vocabulary & Autocorrect
(00:16:06) Sponsor: BetterHelp
(00:17:30) Neuralink, Brain-Machine Interfaces & Augmentation Ethics
(00:22:21) Avatars, Facial Expressions & Non-Verbal Communication
(00:25:48) Sponsor: AG1
(00:27:12) Stuttering, Anxiety & Speech vs Language
(00:30:18) Tool: Stuttering Therapy & Auditory Feedback
(00:31:50) Recap & Acknowledgments
Disclaimer & Disclosures
Learn more about your ad choices. Visit megaphone.fm/adchoices
0 Recall Sets0 enrichment items0 recommended
Sign in to favorite
Listen — make it stick
0:00 / 33:04Speed 1×⤢ Companion mode
React at the exact second
Moments
Sign in to comment on this exact moment.
Sign in to joinLoading the timeline…
Recall — what you keep
+ Author a Recall SetRecall Sets
No Recall Sets here yet — be the first to anchor this episode's sharpest moments.
Enrichment
No enrichment published yet — links, notes, and corrections are still being prepared (and pass human review before they land here). Add the first yourself.
Sign in to add a link, note, or media →Episode discussion
Members in the knowOpening the room…