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Essentials: Using Your Nervous System to Enhance Your Immune System
Sep 25, 2025 · 39 min
In this Huberman Lab Essentials episode, I explain how the immune system defends against infection and describe the relationship between the immune and nervous systems.
I discuss the immune system's three primary layers of defense, emphasizing how each contributes to protection from infection. I share practical tools to enhance immune function and accelerate recovery from sickness, including specific breathing patterns, sleep positioning and targeted supplementation. I also explore the powerful mind-body connection, showing how mindset and nervous system activation can directly influence the body's ability to heal.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
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LMNT: https://drinklmnt.com/huberman
Timestamps
(0:00) Immune System & Nervous System
(0:33) Immune System 101, Innate & Adaptive Immune Systems
(8:03) Mucus & Microbiome, Tools: Nasal Breathing; Avoid Eyes; Ingest Fermented Foods
(10:57) Sponsor: AG1
(12:04) Sickness Behavior & Vagus Nerve, Fever, Photophobia, Rest
(16:43) Humoral Factors, Inflammatory Cytokines
(18:14) Sleep & Enhancing Immune System, Glymphatic System, Tool: Elevate Feet
(21:12) Sponsor: LMNT
(22:44) Stress & Inflammation, Tool: Early Symptoms & Cyclic Hyperventilation
(31:09) Positive Mindset & Immune Function, Dopamine
(34:03) Electroacupuncture, Fascia, Catecholamines & Inflammation
(36:22) Accelerating Recovery, Medication, Tool: Spirulina & Rhinitis
(38:34) Recap & Key Takeaways
Disclaimer & Disclosures
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